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ORIGINAL ARTICLE
Year : 2016  |  Volume : 5  |  Issue : 2  |  Page : 154-156

Congenital von Willebrand factor deficiency in single Iraqi teaching hospital: A descriptive study


Department of Hemophilia, Children Welfare Teaching Hospital, Medical City, Baghdad, Iraq

Correspondence Address:
Obeida Amir Abid
Children Welfare Teaching Hospital, Medical City, Baghdad
Iraq
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/2072-8069.198088

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Background: Von Willebrand disease (vWD) is a common, inherited hemorrhagic disorder caused by a deficiency or dysfunction of the protein von Willebrand factor (vWF). Objectives: The aim of this study is to assess the diagnosis and treatment of vWD in a single Iraqi teaching hospital. Patients and Methods: This descriptive study was conducted on 778 patients with bleeding tendency, 107 patients were diagnosed to have vWD, and from the first of October 2013 to the first of August 2015. The diagnosis of the disease was made by a wide spectrum of characteristics including family history, clinical manifestations, and laboratory tests. Results: The common manifestations of the disease at the time of the diagnosis were epistaxis (39.2%), gum bleeding (24.2%), and menorrhagia (23.4%) in female patients. The age of patients at time of presentation was between 1 and 10 years. Family history was positive in most patients. Hepatitis C was rare in the patients after cryoprecipitate administration. Conclusions: It is a common inherited hemorrhagic disease in Iraq, mostly presented as minor bleeding involving mainly mucocutaneous regions which appears at an early childhood with positive family history in most cases.


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