| ORIGINAL ARTICLE |
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| Year : 2022 | Volume
: 11
| Issue : 2 | Page : 118-124 |
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A role of interim positron emission tomography/computed tomography scan in the management of Hodgkin lymphoma: A single-center study in a developing country
Saya Azeez1, Ahmed Khudair Yassin2, Nawsherwan S Mohammad3, Kawa M Hassan2, Zeki A Mohamed4, Ranan Kardagh Polus5, Hawar Gh. Khudhur1
1 Trainee at Kurdistan Higher Council of Medical Specialties/ Clinical Hematology, Nanakali Hospital – Erbil - Kurdistan Region, Iraq
2 Department of Medicine, College of Medicine, Hawler Medical University, Erbil, Kurdistan Region, Iraq
3 Laboratory Hematopathologist- Nanakali Hospital-Erbil-Kurdistan Region, Duhok, Kurdistan Region, Iraq
4 Department of Medicine, College of Medicine, University of Duhok, Duhok, Kurdistan Region, Iraq
5 Kurdistan Higher Council of Medical Specialties/ Head of Pathology Council, Erbil, Kurdistan Region, Iraq
Correspondence Address:
Dr. Saya Azeez
Nanakali Hospital, Erbil, Kurdistan Region
Iraq
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/ijh.ijh_27_22
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BACKGROUND: The Hodgkin lymphoma (HL) showed a good prognosis in Erbil city. However, a number of deaths were reported. The monitoring and treatment strategies of HL had improved in the last decade.
AIMS: The aims of this study were to evaluate the prognostic value of interim positron emission tomography/computed tomography (PET/CT) scan in HL patients and predicting the survival outcome in addition to effect on progression-free survival (PFS) of HL patients.
PATIENTS AND METHODS: A retrospective cross-sectional study was conducted in Nanakali Hospital in Erbil city, Kurdistan region, Iraq, through reviewing data of patients with HL from January 1, 2014, to December 31, 2019, on a sample of 75 HL patients. The diagnosis of HL was accomplished by the physician regarding lymph node biopsy by the World Health Organization criteria. The PET/CT scan was done after two treatment cycles. PET/CT of HL patients was done in a private center in Erbil city (Media Diagnostic Center).
RESULTS: The mean overall survival duration of HL patients was 5.39 years with an overall survival rate of 92%, and the mean PFS duration of HL patients was 5.04 years with PFS rate of 76%. The mean overall survival of HL patients with positive interim PET/CT (4 years and rate 75%) was lower than the mean overall survival of HL patients with negative interim PET/CT (7.2 years and rate of 95.2%) with a significant difference (P < 0.001).
CONCLUSIONS: The interim PET/CT scan is useful in prognosis of patients with HL and predicting overall survival and mortality.
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